EDC projects are organized into divisions and centers of various sizes. The centers address specific challenges and build upon upon collaborations among staff members and between EDC and its partners. This center-based structure provides EDC with the flexibility to respond quickly to new opportunities and to meet a variety of complex challenges.

• Applied Research and Innovation (ARI)
• Center for Children and Technology (CCT)
• Center for Online Professional Education (COPE)
• Regional Educational Laboratory Northeast and Islands (REL-NEI)
• Education, Employment, and Community Programs (EEC)
  • Community Development
  • Community, Technology, and Learning
  • Gender, Diversities, and Technology
  • Literacies in Education and Health
  • Workforce and Human Development
• Health and Human Development Programs (HHD)
  • Center for College Health and Safety
  • Center for Research on High Risk Behavior
  • Center for School and Community Health Programs
  • Center for the Study and Prevention of Injury, Violence, and Suicide
  • CSAP's Northeast Center for the Application of Prevention Technologies
  • HHD Global Programs
• International Education Systems (IES)
• Mathematics Learning and Teaching (MLT)
  • Center for Mathematics Education (CME)
  • Center for the Development of Teaching (CDT)
• Center for Applied Ethics (CAE)
• Center for Children & Families (CC&F)
• Center for Educational Resources and Outreach (ERO)
• Center for Family, School, and Community (FSC)
• Center for Leadership and Learning Communities (CLLC)
• Center for Science Education (CSE)
• Global Learning Group (GLG)